Ubudahangarwa bw'abaturage "barashobora" gukenera urukingo rwa COVID-19

Curtis J. Patient webinar: Urukingo rwa COVID-19 no kuvura. Orateur: Fondasiyo yubushakashatsi bwa rubagimpande. Gicurasi 11, 2021 (Ikibazo Cyibibazo).
Curtis J. Patient webinar: Urukingo rwa COVID-19 no kuvura. Orateur: Fondasiyo yubushakashatsi bwa rubagimpande. Gicurasi 11, 2021 (Ikibazo Cyibibazo).
Jeffrey R. Curtis, MD, umuyobozi w’itsinda rishinzwe imirimo y’inkingo ya COVID-19 y’ishuri rikuru ry’Abanyamerika ryita ku ndwara ya rubagimpande, yavuze ko abarwayi bafite ubudahangarwa bazakenera buri gihe gukoresha inkingo za COVID-19 mu gihe kiri imbere.
Curtis, umuganga wa rubagimpande, epidemiologue, akaba n'umwarimu w’ubuvuzi muri kaminuza ya Alabama i Birmingham, yabwiye abari bitabiriye ibirori by’ibibazo biherutse gukorwa na Fondasiyo y’ubushakashatsi ya Rheumatology ko yizera ko umuterankunga wa COVID-19 ushobora kuba rusange muri aba barwayi.
“Birumvikana ko hari siyansi nyinshi, kandi siyanse ihora itera imbere. Ibyo ari byo byose utekereza ko uzi muri uku kwezi, ukwezi gutaha gushobora kuba gutandukanye, kubera iyo mpamvu rero, ndatekereza ko ibyo tuvuga cyangwa tuvuga kuri uyu mugoroba bishobora guhinduka. ”Curtis yabwiye abari bitabiriye iryo huriro. Ati: “Njye ku giti cyanjye ndatekereza ko abantu bashobora gukenera imbaraga. Ntabwo bishobora kuba kuri buri wese, ariko ndatekereza ko bishobora kuba ibisanzwe kubona booster hanyuma ukabikora buri gihe. Irashobora kurangira cyane cyangwa nkurukingo rwibicurane, niba atari buri mwaka, Noneho urabikenera byibuze buri mwaka. ”
Yongeyeho ko bitewe n'ubuvuzi umurwayi ahabwa, abantu bashobora no kungukirwa no gukingira indwara cyangwa gukingirwa inshuro nyinshi.
Curtis yagize ati: "Umuntu umwe mu biganiro yazamuye ikibazo cy'uko bashobora kuba atari urugero cyangwa urukingo bifuzaga, bityo rero bitewe n'ubuvuzi uhabwa, iki ni ikintu cyo kuganira n'ushinzwe ubuzima." Ati: “Ariko ndatekereza cyane ko igitekerezo cyo kuzamura imbaraga gishobora kuba cyiza.”
Tumubajije ku bijyanye n’icyizere cyo gukoresha urukingo rwa Pfizer cyangwa Moderna hamwe n’uwongera ikindi kigo, Curtis yasubije ko yizeye ko abahanga bazasaba ko abantu bakomeza gukoresha uru rukingo nk’urukingo rwa mbere.
Yagize ati: “Birashoboka cyane ko iyi itazaba ubushakashatsi bwimbitse mu gihe cya vuba.” “Nuzuye ibyo niteze. Ugomba gukomera ku nkunga wabonye kuva mu ntangiriro. ”
Curtis yagize icyo avuga kandi ku biyobyabwenge bimwe na bimwe bya rubagimpande, harimo rituximab (Rituxan, Genentech) na mycophenolate mofetil, bishobora kugabanya imikorere y'urukingo rwa COVID-19.
Yagize ati: “Ntekereza ko Rituximab izaba imwe mu miti ishimishije.” Rituximab ifite akamaro kanini mugukuraho selile B no kugora umubiri gukora antibodies. Iki nikintu cyiza mugihe urimo kuvura ikintu na antibodi ushaka kuvanaho, ariko niba ushaka gufasha sisitemu yumubiri kurwanya indwara mugihe kizaza, ntibishobora kuba byiza. ”
Rituximab irashobora kugabanya ubudahangarwa bw'umubiri kurwego runini kuruta ubundi buvuzi bwinshi. Mycophenolate mofetil niyindi. Ati: "Ibi ni ibintu bibiri nshobora gutindiganya cyane, kugira ngo nemeze rwose ko umuntu arinzwe neza na COVID-19."
Nk’uko Curtis abitangaza ngo ibibazo birimo inzitizi za JAK ndetse no kugabanya ingaruka z’inkingo, harimo na ACR COVID-19 Itsinda ry’imirimo y’inkingo ya ACR COVID-19 naryo ryashimishije abantu.
Curtis yagize ati: “Iyi ni yo mpamvu bamwe muri bo bavuga ko, niba bishoboka, igihe gito cyo kwivuza gishobora kuba ari cyiza.” Ati: "Iyi ntabwo ari umuburo rusange, ugomba kubikora uko byagenda kose, ariko hamwe na rubagimpande Vugana na muganga wumurwayi. ACR yabonye ibyifuzo bishya bivuye mu itsinda rishinzwe kuyobora, kandi ibyo byifuzo byatanzwe mu minsi yashize. ”
Ubushakashatsi bushya bwasohotse muri Gut bwerekanye ko abarwayi barwaye amara yakiriye infliximab bagabanutse ku rukingo rwa COVID-19 bakimara guterwa bwa mbere (Remicade, Janssen). Ariko, mugihe umurwayi umwe yaje guhabwa inshuro ya kabiri yo kuvurwa, ubudahangarwa bw'umubiri bwasaga nkibisanzwe.
Nk’uko Curtis abitangaza ngo ibi byongereye igihe cyo kwakira ikinini cya kabiri cyo kuzigama dosiye mu bihugu bimwe na bimwe, atari kuri IBD na infliximab gusa, ahubwo no ku barwayi bafite indwara nyinshi ziterwa na autoimmune no kuvura.
Ati: “Niba utuye mu gihugu kandi Amerika ntabwo ari imwe muri zo, ubwo rero ni ukongera intera kuva ku gipimo cya mbere kugeza ku kigero cya kabiri kugira ngo ukize igipimo kugira ngo buri wese abone ikinini cya mbere. Ntekereza ko, Iki gishobora kuba atari igitekerezo cyiza ku bantu barimo kuvurwa indwara ya immunomodulatory ku ndwara ya Crohn cyangwa lupus, vasculitis, rubagimpande ya rubagimpande cyangwa izindi ndwara. ” Curtis. Ati: “Mubyukuri, ntabwo ari infliximab gusa, ahubwo ni Remicade na [biosimilars] Inflectra na Renflexis. Ndakeka kandi ko ibiyobyabwenge byinshi ari bimwe. ”
Yongeyeho ko ubu hari ubushakashatsi bwinshi ku gisubizo cy’abarwayi barwaye indwara ziterwa na autoimmune ku rukingo rwa COVID-19 nyuma ya dosiye ya mbere n'iya kabiri. Ibisubizo byerekana ko antibodies zuzuye zizakorwa nyuma yurukingo rwuzuye rwinkingo zirangiye. igisubizo.
Curtis yagize ati: “Ubu, hari ubushakashatsi mu bitabo, biga uko bigenda nyuma yo gufata ikinini cya mbere.” Abantu benshi bakingiza inkingo nibyiza, ariko kubantu benshi, ingaruka ntabwo ari nziza cyane. Kubwibyo, ndatekereza ko amakuru yingenzi nize muri zimwe mu nyandiko zandikishijwe intoki nasuzumye ziri mu ruhame rusange, kandi zimwe zanyoherereje rwihishwa, kandi rwose ugomba kwemera ikigereranyo cya kabiri.
Ati: "Ibi ni ukuri cyane cyane niba ufite indwara ya autoimmune cyangwa ukaba wakira imiti igira ingaruka ku budahangarwa, kuko keretse urangije amasomo yose uko yakabaye nkuko byari byitezwe, abantu bamwe bazakomeza guhura n'akaga kandi mbere yuko igisubizo giteganijwe giteganijwe, Babonye igipimo cya kabiri. ” Yongeyeho. Ati: “Noneho, muri rusange, abarwayi bafite rubagimpande basa nkaho barinzwe neza nyuma yo guhabwa inshuro ya kabiri, ariko hari bimwe bidasanzwe.”

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